安坤

ORCID: 0000-0002-2595-9803

Email: ankun615@ahnu.edu.cn & ankun615@aliyun.com

教育经历:

2015.09–2019.06  清华大学  理学博士（生物学）  导师：何伟教授

2007.09–2011.06  山东大学  理学学士（化学）   导师：鲁在君教授

工作经历:

2023.03–至今               安徽师范大学

2019.08–2022.10  博士后研究员   日本理化学研究所（导师：侯召民教授）

2012.09–2015.08  研究助理      清华大学医学院（导师：何伟教授）

发表论文:

1. An, K.; He, W. Rhodium-Catalyzed Enantioselective Intramolecular Hydrosilylation to Access Silicon-Stereogenic Tertiary Hydrosilanes. Chin. J. Org. Chem. 2022, 42, 918–920. (invited highlight)

2. An, K.^‡; Ma, W.^‡; Liu, L. C.; He, T.; Guan, G.; Zhang, Q. W.; He, W. Rhodium Hydride Enabled Enantioselective Intermolecular C–H Silylation to Access Acyclic Stereogenic Si–H. Nat. Commun. 2022, 13, 847.（共同第一作者）

3. Lin, X.‡; An, K.‡; Zhuo, Q.; Nishiura, M.; Cong, X.; Hou, Z. Diastereo- and Enantioselective Hydrophosphination of Cyclopropenes under Lanthanocene Catalysis. Angew. Chem., Int. Ed. 2023, 62, e202308488. (共同第一作者）

4. Zhang, L.^‡; An, K.^‡; Wang, Y.^‡; Wu, Y.-D.; Zhang, X.; Yu, Z.-X.; He, W. A Combined Computational and Experimental Study of Rh-Catalyzed C–H Silylation with Silacyclobutanes: Insights Leading to a More Efficient Catalyst System. J. Am. Chem. Soc. 2021, 143, 3571–3582.（共同第一作者）

5. Zhang, Q. W.^‡; An, K.^‡; Liu, L. C.; Zhang, Q.; Guo, H.; He, W. Construction of Chiral Tetraorganosilicons by Tandem Desymmetrization of Silacyclobutanes/Intermolecular Dehydrogenative Silylation. Angew. Chem., Int. Ed. 2017, 56, 1125–1129.（共同第一作者）

6. Zhang, Q. W.^‡; An, K.^‡; Liu, L. C.; Guo, S.; Jiang, C.; Guo, H.; He, W. Rhodium-Catalyzed Intramolecular C-H Silylation by Silacyclobutanes. Angew. Chem., Int. Ed. 2016, 55,6319–6323.（共同第一作者）

7. Xu, W.; Cong, X.; An, K.; Lou, S.; Li, Z.; Nishiura, M.; Murahashi, T.; Hou, Z. Regio- and Diastereoselective Formal [2+2] Cycloaddition of Allenes with Amino-Functionalized Alkenes via Rare-Earth-Catalyzed Allene C(sp²)–H Activation. Angew. Chem., Int. Ed. 2022,61, e202210624.

8.Lou, S.-J.; Luo, G.; Yamaguchi, S.; An, K.; Nishiura, M.; Hou, Z. Modular Access to Spiro-dihydroquinolines via Scandium-Catalyzed Dearomative Annulation of Quinolines with Alkynes. J. Am. Chem. Soc. 2021, 143, 20462–20471.

9. Ma, W.; Liu, L. C.; An, K.; He, T.; He, W. Rh-Catalyzed Syntheses of Chiral Monohydrosilanes via Intramolecular C-H Functionalization of Dihydrosilanes. Angew. Chem., Int. Ed. 2021, 60, 4245–4251.

10. Yang, C.; Wang, J.; Li, J.; Ma, W.; An, K.; He, W.; Jiang, C. Visible-Light Induced Radical Silylation for the Synthesis of Dibenzosiloles via Dehydrogenative Cyclization. Adv. Synth. Catal. 2018, 360, 3049–3054.

11.Zhang, Q. W.; An, K.; Liu, L. C.; Yue, Y.; He, W. Rhodium-Catalyzed Enantioselective Intramolecular C–H Silylation for the Syntheses of Planar-Chiral Metallocene Siloles. Angew. Chem., Int. Ed. 2015, 54, 6918–6921.

12.Zhang, Q. W.; An, K.; He, W. Catalytic Synthesis of π-Conjugated Silole through Si–C (sp³) Bond Activation. Synlett 2015, 26, 1145–1152.

13. Zhang, Q. W.;An, K.; He, W. Rhodium-Catalyzed Tandem Cyclization/Si-C Activation Reaction for the Synthesis of Siloles. Angew. Chem., Int. Ed. 2014, 53, 5667–5671.

书籍章节:

α-Silyl Alcohols, Ethers, and Amines (Update 2020), Zhang, Q. W., An, K., He, W. Science of Synthesis Knowledge Updates, 2020, 3, 1.